We are working on making
changes on the labels.
Active Heart Scientific Statement & References
As a cardiologist I have had the opportunity to face multiple cardiac problems
specifically coronary artery disease. After extensive review of the literature
available, I have put together what I think is an excellent prevention formula that
includes vitamins, omega 3 fatty acids and other substances.
Omega 3 polyunsaturated fatty acids are associated with lower risk of coronary
disease particularly death (1), and reduced total and coronary mortality in men who
had suffered a myocardial infarction (2). They also improve large artery
endothelium-dependent dilation in subjects with hypercholesterolemia (3). There
is epidemiological and clinical trial evidence supporting its role as cardio
protective agents (4). This effect has also been demonstrated in women (5).
Beta-sitosterol is a plant sterol that lowers cholesterol levels up to 10% by
reducing intestinal absorption and current evidence is sufficient to promote its use
for lowering LDL cholesterol for persons at increased risk for coronary disease (6).
L-Arginine is an amino acid that acts as the precursor of Nitric Oxide (NO), which is
formed in the endothelial cell and acts as vasodilator by relaxing the smooth
muscle cells of the media of arteries and arterioles of the heart (7). Its discovery
lead to the noble prize of medicine. Patients with atherosclerosis as well as with
risk factors for coronary artery disease have an impaired release of this substance.
Its administration prevents the development of nitrate tolerance (8).
B complex vitamins including folic acid reduce the homocysteine level, a
recognized risk factor for coronary disease. Elevated concentration of
homocysteine has been associated with increased risk of acute events such as
myocardial infarction and stroke. The homocysteine level may be lowered safely
and effectively with diet modification and/or vitamin supplementation with folic
acid, vitamins B12 & B6 (9). Niacinamide raises HDL and lowers LDL cholesterol and
also lowers lipoprotein (a), a newly recognized risk for coronary disease.
Vitamin E has been linked to confusing outcomes for the last 15 years of research.
However most recent analysis has concluded the lack of major protective effect of
vitamin E supplementation, taken in moderately high dosage, against complications
in atherosclerosis and overall cancer incidents. In fact there are even some hints
that vitamin E, in excess of normal daily intake, may slightly increase the risk of
ischemic events (10). This effect appears to be dose dependent and it starts to
increase for dosages greater than 400 iu per day. It was also noted at small
mortality benefit with low dosage vitamin E supplementation. We have chosen to
add a very small amount of natural vitamin E to our supplement.
Alpha Lipoic Acid is a special antioxidant that helps to deactivate cell-damaging
particles called, “free radicals”. It works with other antioxdants such as vitamins A,
C and E, “recycling” them and thus making them much more effective (11).
Our formula would not be complete if we used second rated raw materials. We do
not take short cuts in our manufacturing process. We pride ourselves with using
the following standard:
All raw materials used in Vital Complex are tested according to Good
Manufacturing Procedures. Strict quality control ensures that each batch of raw
material is tested for contaminants such as bacteria, heavy metals, pesticides and
herbicides. All our oils (EPA) are purity tested and utilize cold-water fish such as
sardines, anchovies and mackerel to provide a pure, rich source of omega -3’s.
Only the highest quality fillers, binders and excipients are used in the manufacture
of our supplements.
Supplements are further tested for dissolution time and degradation of ingredients
up to and beyond the expiration date to ensure full potency as stated on the label.
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
1 Albert CM, Campos H, Stampfer MJ, et al. Blood levels of long chain n-3 fatty acids and the risk of sudden death.
N Engl J Med 2002;346:1113-8.
2 GISSI-Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E in
11,324 patients with myocardial infarction: results of the GISSI-Prevenzione trial. Lancet 1999;354:447-55.
3 Goodfellow J, Bellamy MF, Ramsey MW, et al. Dietary supplementation with marine omega-3 fatty acids improve
systemic large artery endothelial function in subjects with hypercholesterolemia. J Am Coll Cardiol 2000;35:265-70.
4 Harper CR, Jacobson TA. The fats of life, the role of omega-3 fatty acids in the prevention of coronary heart
disease. Arch Intern Med 2001;161:2185-92.
5 Hu FB, Bronner L, Willett WC, et al. Fish and omega-3 fatty acid intake and risk of coronary heart disease in
women. JAMA 2002; 287:1815-21.
6 Katan MB, Grundy SM, Jones P, et al. Efficacy and safety of plant stanols and sterols in the management of blood
cholesterol levels. Mayo Clin Proc.
2003;78:965-78.
7 Xu WM, Liu LZ. Nitric Oxide: from a mysterious labile factor to the molecule of the Nobel Prize. Recent progress in
nitric oxide research. Cell Res. 1998;8:251-58.
8 Parker JO, Parker JD, Caldwell RW, et al. The effect of supplemental L-Arginine on tolerance development during
continuous transdermal nitroglycerin therapy. J Am Coll Cardiol 2002;39:1199-203.
9 Gauthier GM, Keevil JG, McBride PE. The association of homocysteine and coronary artery disease. Clin Cardiol
2003;26:563-8.
10 Miller ER, Pastor-Barriuso R, Dalal D, et al. Meta-analysis: Hish-dosage vitamin E supplementation may increase
all-cause mortality. Ann Intern Med
2005;142:37-46.
11 Thiol homeostasis and supplements in physical exercise.1 American Journal of Clinical Nutrition, Vol. 72, No. 2,
653s-669s, August 2000
At Vital Complex LLC we are committed to delivering high quality customer service. Please read on for more details about
our procedures and how we can best serve you. If you don't find your concern addressed here, feel free to contact us by e-
mail or mail.
Please allow 10 to 14 days delivery on all orders. For special deliveries, please contact a sales rep directly:
sales@vitalcomplex.com
Contents:
1. What is your online return and exchange policy?
2. What if I don't have a packing receipt?
3. What is your privacy policy?
4. Can I order merchandise from the web site over the phone?
5. The item I bought yesterday is now on sale. Can I get the lower price?
6. What are my payment options at Vital Complex LLC?
7. Do you ship orders outside the U.S.?
8. Will my order arrive by Christmas?
9. In summary
________________________________________
What is your online return and exchange policy?
An original packing receipt dated within 30 days is required for all returns and exchanges.
You can make returns or exchanges via mail with an original Vital Complex LLC packing receipt or an online payment
receipt. All returns must be new, unused and contain all original product packaging and accessories. Other restrictions
may apply.
Holiday and seasonal merchandise on clearance at time of return will be refunded at the clearance price.
All other returns or exchanges — including those without receipt — will be charged a 25% restocking fee. Sorry, but
shipping charges will not be refunded.
To return a Vital Complex LLC purchase by mail: Pack the item and include all product packaging and accessories.
Enclose your original packing receipt or an online payment receipt and be sure to complete all necessary information.
Ship your package to:
Vital Complex LLC
124 Locust Ave.
Dumont, NJ 07628
ATTN: Returns
________________________________________
What if I don't have a packing receipt?
We want to ensure your Vital Complex LLC returns and exchanges are fast and convenient. If you misplaced your packing
receipt, in most cases you can still make a return or exchange by mail. Any Vital Complex LLC sales rep can look up and
find most orders made online by credit card within the last 90 days. You can also print a payment receipt made at the
time of payment online.
If you misplaced your packing receipt and want to mail your return, please include the following:
The item you are returning, including all product packaging and accessories. A note with your name, address and order
number. Ship your package to:
Vital Complex LLC
124 Locust Ave.
Dumont, NJ 07628
ATTN: Returns
For manufacturers' warranty, repair information, or exchanges please email us.
________________________________________
What is your privacy policy?
We are committed to protecting your privacy. We use the information we collect on the site to make shopping at Vital
Complex LLC possible and to enhance your overall shopping experience. We do not sell, trade or rent your personal
information to others without your permission. We guarantee the security of your information. Please read the complete
Private policy on our site.
________________________________________
Can I order merchandise from the web site over the phone?
Yes. While shopping at Vital Complex LLC is safe and secure, we realize that some of our guests would prefer to order
via fax. We invite you to browse through our site and then fax us (201)- 387-1843 or go to this link to see what stores are
selling Vital Complex products Click here or: email us if you have any questions. Sales@vitalcomplex.com
________________________________________
________________________________________
The item I bought yesterday is now on sale. Can I get the lower price?
If we advertise a lower price in the week of, or in the week following your full-price purchase, simply email us. We will
refund you the difference. Sorry, no price adjustments can be made for clearance pricing or items purchased on other
websites.
________________________________________
What are my payment options at Vital Complex LLC?
You can pay with a credit card online. The credit cards we accept are Visa, MasterCard and American Express.
We will also accept fax orders and checks. Please go through the checkout process without clicking submit. This will
calculate a grand total for you. (As soon as your check clears, we will mail your item.)Then print the Shopping Cart page
and remit payment to:
(to obtain address please email us your zip code and we will email you the address. We have different warehouses around
the country.)
________________________________________
How does Vital Complex LLC protect my credit card information?
We do not sell your information to any third party and we use a secure server.
We know that offering a safe and secure shopping experience is one of the most important things we do. We use Secure
Sockets Layering (SSL) to encrypt all of your personal information including your credit card number. Additional
information is available in our Privacy Policy.
________________________________________
Do you ship orders outside the U.S.?
Yes, however we do charge an additional amount for shipping and handling fee.
________________________________________
Will my order arrive by Christmas?
If your order is placed at least 3 weeks in advance of Christmas, it will arrive before Christmas. Please note that any
backordered items will be shipped within 30 days, as indicated during checkout.
________________________________________
In summary
We are committed to providing high quality customer service and will make every effort to accommodate your needs.
Return your Vital Complex LLC goods within 30 days for a full refund if item is unopened. Please see our specific details
on returns on our site. You can order via the web site using a Visa or Mastercard. We use a secure ordering procedures,
and you can find out more about our ordering policies in our Privacy Policy.